QuickView for fibronectin 1;jsessionid=B38A3EECA01A266E8681DFDEAF005F3F;jsessionid=A5F66451C6588CF0AA1BCFBE5F1AD908 (gene)
- Gene Symbol:
- Fn1
Rattus norvegicus - Full name:
- fibronectin 1
- Synonyms:
- FIBNEC, fn-1, fibronectin, FN, fibronectin 2, fibronectin 3
- Genomic Location:
- Chr 9: 70702181-70771155
- Description:
-
extracellular matrix component; may play a role in fibrosis and tumor metastasis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AAANWWTGC_UNKNOWN , ACAWYAAAG_UNKNOWN , SRY_02 , STAT_01 , SOX9_B1 , STAT5A_03 , STAT6_01 , STAT4_01 , AP3_Q6 , STAT_Q6
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
structural molecule activity | enzyme activator activity | cation binding | enzyme binding | protein-containing complex binding | disordered domain specific binding | peptidase activator activity | signaling receptor binding | carbohydrate derivative binding | molecular function regulator | mercury ion binding | chaperone binding | protein domain specific binding | anion binding | identical protein binding | ion binding | integrin binding | heparin binding | cell adhesion molecule binding | protein binding | glycosaminoglycan binding | transition metal ion binding | enzyme regulator activity | protease binding | metal ion binding | protein C-terminus binding | extracellular matrix structural constituent
GO Biological Process
regulation of ERK1 and ERK2 cascade | cell morphogenesis | positive regulation of locomotion | extracellular structure organization | response to cytokine | response to interleukin-1 | cellular response to glucose stimulus | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | response to lipopolysaccharide | negative regulation of peptide secretion | enzyme activator activity | cellular response to platelet-derived growth factor stimulus | regulation of cell development | regulation of localization | cell-substrate adhesion | regulation of programmed cell death | response to hormone | regulation of cell shape | negative regulation of cellular process | positive regulation of developmental process | substrate adhesion-dependent cell spreading | response to metal ion | cell differentiation | positive regulation of fibroblast proliferation | defense response | nervous system development | response to drug | cellular chemical homeostasis | positive regulation of axonogenesis | neurogenesis | glucose homeostasis | positive regulation of cell adhesion | negative regulation of protein secretion | positive regulation of cellular component movement | generation of neurons | response to antibiotic | mesenchyme development | interaction with symbiont | blood vessel morphogenesis | cellular process | regulation of cell motility | localization | cellular homeostasis | regulation of chemotaxis | positive regulation of substrate-dependent cell migration, cell attachment to substrate | negative regulation of apoptotic process | negative regulation of secretion | regulation of proteolysis | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | response to inorganic substance | negative regulation of establishment of protein localization | response to peptide hormone | tissue development | regulation of cell differentiation | interspecies interaction between organisms | response to prostaglandin | cell junction assembly | autonomic nervous system development | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | cellular response to prostaglandin stimulus | gliogenesis | negative regulation of cytokine secretion | cellular response to molecule of bacterial origin | peptidase activator activity | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | response to transforming growth factor beta | cellular response to metal ion | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | vasculature development | cellular response to vascular endothelial growth factor stimulus | mesenchymal cell development | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | response to ozone | regulation of cell proliferation | tube morphogenesis | response to peptide | response to glucose | cellular response to inorganic substance | response to alcohol | cardiovascular system development | positive regulation of proteolysis | response to molecule of bacterial origin | response to ischemia | extracellular matrix organization | negative regulation of transport | regulation of protein transport | regulation of cellular component size | cellular component assembly | regulation of axon extension | protein modification process | regulation of peptide transport | peptide cross-linking | regulation of cell adhesion | embryo development | response to iron ion | macromolecule modification | molecular function regulator | neural crest cell migration involved in autonomic nervous system development | blood vessel development | locomotion | response to nitrogen compound | response to BMP | calcium-independent cell-matrix adhesion | cellular response to hormone stimulus | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of secretion by cell | positive regulation of neuron projection development | multicellular organism development | response to activity | cell migration | cellular glucose homeostasis | cellular response to peptide hormone stimulus | regulation of peptidase activity | regulation of MAPK cascade | response to fatty acid | regulation of axonogenesis | regulation of catalytic activity | regulation of phosphorylation | wound healing | cellular response to prostaglandin E stimulus | regulation of neuron differentiation | regulation of gene expression | positive regulation of chemotaxis | response to prostaglandin E | response to ketone | response to lipid | cellular response to peptide | negative regulation of cytokine production | positive regulation of cellular metabolic process | response to mercury ion | regulation of nitrogen compound metabolic process | regulation of cell migration | glial cell migration | regulation of cell-substrate adhesion | positive regulation of cell projection organization | cell-substrate junction assembly | response to corticosteroid | regulation of cellular component movement | endoderm formation | response to oxidative stress | positive regulation of hydrolase activity | positive regulation of cell differentiation | acute-phase response | stem cell differentiation | response to platelet-derived growth factor | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | angiogenesis | cell morphogenesis involved in differentiation | cellular response to angiotensin | neural crest cell migration | response to bacterium | regulation of cellular metabolic process | cellular response to mercury ion | inflammatory response | cellular response to amyloid-beta | regulation of protein metabolic process | homeostatic process | positive regulation of cell proliferation | response to monosaccharide | regulation of protein phosphorylation | regulation of locomotion | cellular response to fatty acid | embryonic morphogenesis | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | positive regulation of axon extension | regulation of cytokine secretion | response to angiotensin | negative regulation of transforming growth factor-beta secretion | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of fibroblast proliferation | regulation of establishment of protein localization | regulation of growth | response to organic substance | response to wounding | regulation of intracellular signal transduction | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | mesenchymal cell differentiation | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | chemical homeostasis | regulation of secretion | cell adhesion | organic substance metabolic process | animal organ development | response to reactive oxygen species | positive regulation of cell-substrate adhesion | regulation of protein secretion | regulation of phosphate metabolic process | cell activation | stem cell development | anatomical structure formation involved in morphogenesis | regulation of cell communication | positive regulation of developmental growth | integrin activation | positive regulation of growth | response to amyloid-beta | cell-matrix adhesion | response to organic cyclic compound | interaction with other organism via secreted substance involved in symbiotic interaction | cell development | regulation of developmental growth | cellular protein metabolic process | regulation of cell size | enzyme regulator activity | endodermal cell differentiation | regulation of cytokine production | endoderm development | anatomical structure morphogenesis | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | developmental process | cellular response to interleukin-1 | regulation of cell growth | cellular protein modification process | tube development | regulation of transport | response to organonitrogen compound | neural crest cell differentiation | formation of primary germ layer | positive regulation of metabolic process | ossification | positive regulation of neuron differentiation | cellular response to BMP stimulus | regulation of cell projection organization | acute inflammatory response | gastrulation | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | response to carbohydrate | response to steroid hormone | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | circulatory system development | carbohydrate homeostasis | neural crest cell development | regulation of cellular component organization | response to other organism | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
endoplasmic reticulum-Golgi intermediate compartment | intracellular membrane-bounded organelle | apical plasma membrane | extracellular matrix | basement membrane | cell | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | apical part of cell | fibrinogen complex | protein-containing complex | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | intracellular | membrane
